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Transferrin (TRF) Rapid Test 

Transferrin (TRF) is a plasma protein that transports iron through the blood to the liver, spleen and bone marrow. Transferrin mainly exists in the plasma, and there is no transferrin in the digestive tract of healthy person.But, some disease will cause gastrointestinal bleeding, e g: Esophageal diseases, Colorectal cancer, Small intestinal diseases. Because of gastrointestinal bleeding, transferrin may be leaked into gastrointestinal tract and then discharged with the faeces. 

Transferrin is stable in faeces and a good marker to detect gastrointestinal bleeding.

Principle

Biologic. material Category Test duration Category
Feces IVD Other 5 min Tumor markers

 The TRF Rapid Test Device (Feces) detects human transferrin through visual interpretation of color development on the internal strip. Anti-human transferrin antibodies are immobilized on the test region of the membrane. During testing, the specimen reacts with anti-human transferrin antibodies conjugated to colored particles whichprecoated onto the sample pad of the test. The mixture then migrates through the membrane by capillary action and interacts with reagents on the membrane. If there is sufficient human transferrin in the specimen, a colored band will form at the test region of the membrane. The presence of this colored band indicates a positive result, while its absence indicates a negative result. The appearance of a colored band at the control region serves as a procedural control, indicatingthat the proper volume of specimen has been added and membrane wicking has occurred.