Toxoplasmosis IgM/IgG Test
Toxoplasmosis is a common parasitic infection caused by an obligate intracellular protozoan, T. gondii, which is widespread throughout the World. Although T. gondii infection is generally asymptomatic in healthy adults, it may lead to severe conditions in immunosuppressed individuals including patients with AIDS and the developing fetus. T. gondii infection in the immunosuppressed patients causes encephalitis, pneumonia, and disseminated infection.
Transplacental transmission of the parasite may occurs during the first two trimesters of pregnancy and can severely damage the fetus, which eventually causes irreversible neurological damages, neonatal malformations, blindness, or fetal death.
Therefore, diagnosis of toxoplasmosis presents an essential measure for the disease control. Various methods can be achieved including indirect fluorescent-antibody test, tissue culture, PCR, and rapid immunoassay. Serological diagnosis can establish current and past infections with T. gondii. The antibody response to T. gondii is highly specific. Detection of IgG antibodies to T. gondii indicates that individuals have past infections, while detection of IgM antibodies to T. gondii signifies a current and acute infection.
The TOXO IgG/IgM Rapid Test Device (Whole Blood/Serum/Plasma) is a lateral flow immunoassay to differentially detect the IgG and IgM antibodies specific to T. gondii, and will present a presumptive diagnosis of T. gondii infection.