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Principle

Biologic. material Category Test duration Category
serum, plasma, whole blood IVD Other 10 min Tumor markers

The HL-Ferritin Rapid Test Device (Whole Blood/Serum/Plasma) detects ferritin through visual interpretation of color development on the internal strip. Ferritin antibodies are immobilized on the test region of the membrane. During testing, the specimen reacts with ferritin antibodies conjugated to colored particles and precoated onto the conjugated pad of the test. The mixture then migrates through the membrane by capillary action, and interacts with reagents on the membrane. If there are sufficient ferritin in the specimen, a colored band will form at the test region of the membrane. A test band (T) singal weaker than the reference band (R) indicates that the ferritin level in the specimen is between 200-400 ng/mL. A test band (T) signal equal or close to the reference band (R) indicates that the ferritin level in the specimen is approximately 400 ng/mL. The appearance of a colored band at the control region serves as a procedural control, indicating that the proper volume of specimen has been added and membrane wicking has occurred.

Ferritin HL-FRT Rapid Test

Ferritin is a ubiquitous intracellular protein that stores iron and releases it in a controlled fashion. The protein is produced by almost all living organisms, including bacteria, algae and higher plants, and animals. In humans, it acts as a buffer against iron deficiency and iron overload. Ferritin is a globular protein complex consisting of 24 protein subunits and is the primary intracellular iron-storage protein in both prokaryotes and eukaryotes, keeping iron in a soluble and non-toxic form. Ferritin that is not combined with iron is called apoferritin.