lomina.ch

MYO

MYO is early sensitive marker to diagnose early acute myocardium infarction(AMI).

Myoglobin Rapid Test

Myoglobin (MYO) is a heme-protein normally found in skeletal and cardiac muscle with a molecular weight of 17.8 kDa. It constitutes about 2 % of total muscle protein and is responsible with transporting oxygen within the muscle cells. When the muscle cells are damaged, Myoglobin is released to the blood rapidly due to its relatively small size. Following the death of tissue associated with MI, Myoglobin is one of the first markers to rise above normal levels. The level of Myoglobin increases measurably above baseline within 2-4 hours post-infarct, peaking at 9-12 hours, and returning to baseline within 24-36 hours. A number of reports suggest the measurement of Myoglobin as a diagnostic aid in confirming the absence of myocardial infarction with negative predictive values of up to 100% reported at certain time periods after onset of symptoms.

The Myoblobin Rapid Test Device is a simple test utilizing a combination of anti-Myoglobin antibody coated particles and capture reagent to detect Myoglobin in whole blood, serum or plasma. The minimum detection level is 50 ng/mL

Principle

Biologic. material Category Test duration Category
serum, plasma, whole blood IVD Other 10 min Cardio

 

The Myoblobin Rapid Test Deviceis a qualitative, membrane based immuno­assay for the detection of Myoglobin in whole blood, serum or plasma. The membrane is pre-coated with capture reagent on the test line region of the test. During testing, the whole blood, serum or plasma specimen reacts with the particle coated with anti-Myoglobin antibodies. The mixture migrates upward on the membrane chromatographically by capillary action to react with capture reagent on the membrane and generates a colored line. The presence of this colored line in the test line region indicates a positive result, while its absence indicates a negative result. To serve as a procedural control, a colored line will always appear in the control line region indicating that proper volume of specimen has been added and membrane wicking has occurred.